TAMEing ADPKD with metformin: safe and effective?
نویسندگان
چکیده
The biguanide metformin has been safely and widely used in the treatment of type 2 diabetes mellitus for decades. Preclinical studies have suggested that it may a role slowing disease progression autosomal dominant polycystic kidney disease. In this issue, Perrone et al. report results from Trial Administration Metformin PKD (TAME PKD) study, phase randomized controlled trial investigating safety tolerability patients early stages We discuss implications these findings how they relate to major 3 will start later 2021.
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ژورنال
عنوان ژورنال: Kidney International
سال: 2021
ISSN: ['0085-2538', '1523-1755']
DOI: https://doi.org/10.1016/j.kint.2021.07.021